This presentation explores the potential link between immune function, autoimmune disorders, and autism spectrum disorder (ASD). The discussion highlights historical observations dating back to Leo Kanner’s 1943 paper, which noted immune-related symptoms in autistic children. More recent studies have found increased rates of autoimmune conditions, such as hypothyroidism and rheumatoid arthritis, in the families of autistic individuals, suggesting a genetic and environmental interplay. The Lurie Center’s research investigates whether maternal immune activation during pregnancy could impact fetal brain development, contributing to ASD. The session underscores the need for further studies to confirm these findings and refine treatment approaches.

