httphttps://pmc.ncbi.nlm.nih.gov/articles/PMC9355470/#abstract1
This article offers a comprehensive and well‑balanced overview of how the gut microbiome interacts with autism spectrum disorder (ASD), blending mechanistic insights with therapeutic considerations. It reviews robust evidence on microbiota–gut–brain signaling pathways, microbial dysbiosis in ASD, and the roles of diet, probiotics, antibiotics, and fecal microbiota transplantation. The authors effectively synthesize data from preclinical models and clinical studies, highlighting both opportunities and limitations of microbiome‑targeted interventions. Its emphasis on clear mechanisms, coupled with a careful discussion of regulatory hurdles and safety, makes this a must‑read for researchers and clinicians exploring novel, evidence‑based ASD therapies.
